A night of wild partying ends in disaster when janitor Kenneth falls into a drug-induced coma. Fearing their future reputations, a group of med students abandon the body outside a hospital.
Racked by guilt, good girl Catherine (Arielle Kebbel, Gilmore Girls) secretly attempts to revive him, but administers a rare chemical allowing Kenneth to possess random strangers' bodies and exact revenge on those who wronged him. Can Catherine find a cure before she's next?